{"id":3697,"date":"2023-12-07T06:29:11","date_gmt":"2023-12-07T06:29:11","guid":{"rendered":"https:\/\/hedayatcentre.org\/?p=3697"},"modified":"2023-12-07T06:30:54","modified_gmt":"2023-12-07T06:30:54","slug":"vitamin-b12-emerges-as-key-player-during-cellular-reprogramming","status":"publish","type":"post","link":"https:\/\/hedayatcentre.org\/fa\/3697\/vitamin-b12-emerges-as-key-player-during-cellular-reprogramming\/","title":{"rendered":"\u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 B12 \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u0628\u0627\u0632\u06cc\u06af\u0631 \u06a9\u0644\u06cc\u062f\u06cc \u062f\u0631 \u0637\u0648\u0644 \u0628\u0631\u0646\u0627\u0645\u0647\u200c\u0631\u06cc\u0632\u06cc \u0645\u062c\u062f\u062f \u0633\u0644\u0648\u0644\u06cc \u0638\u0627\u0647\u0631 \u0645\u06cc\u200c\u0634\u0648\u062f"},"content":{"rendered":"\n<p><strong>\u0628\u0627 \u062a\u062c\u0632\u06cc\u0647 \u0648 \u062a\u062d\u0644\u06cc\u0644 \u0627\u062b\u0631 \u0645\u062e\u062a\u0644 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\u067e\u0631\u062a\u0648\u0627\u0646\u06cc \u0631\u0627 \u0628\u06cc\u0627\u0646 \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f. \u0645\u062a\u0639\u0627\u0642\u0628\u0627\u064b\u060c \u0627\u06cc\u0646 \u0633\u0644\u0648\u0644\u200c\u0647\u0627 \u062f\u0631 \u0646\u0647\u0627\u06cc\u062a \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u0646\u062f \u0628\u0627\u0639\u062b \u0627\u06cc\u062c\u0627\u062f \u062a\u0631\u0627\u062a\u0648\u0645 \u062f\u0631 \u0627\u0646\u062f\u0627\u0645\u200c\u0647\u0627\u06cc \u0645\u062e\u062a\u0644\u0641 \u0634\u0648\u0646\u062f. \u0627\u0632 \u0633\u0648\u06cc \u062f\u06cc\u06af\u0631\u060c \u0628\u06cc\u0627\u0646 \u06a9\u0648\u062a\u0627\u0647\u200c\u0645\u062f\u062a OSKM \u06a9\u0647 \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0628\u0631\u0646\u0627\u0645\u0647\u200c\u0631\u06cc\u0632\u06cc \u0645\u062c\u062f\u062f \u062c\u0632\u0626\u06cc \u0634\u0646\u0627\u062e\u062a\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u0627\u0645\u06a9\u0627\u0646 \u062c\u0648\u0627\u0646\u200c\u0633\u0627\u0632\u06cc \u0633\u0644\u0648\u0644\u06cc \u0631\u0627 \u0628\u062f\u0648\u0646 \u0628\u0647 \u062e\u0637\u0631 \u0627\u0646\u062f\u0627\u062e\u062a\u0646 \u0647\u0648\u06cc\u062a \u0633\u0644\u0648\u0644\u06cc \u0641\u0631\u0627\u0647\u0645 \u0645\u06cc\u200c\u06a9\u0646\u062f.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0645\u0646\u0627\u0628\u0639<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Takahashi, K. &amp; Yamanaka, S. Cell 126, 663-676 (2006).<\/li>\n\n\n\n<li>\u0622\u0628\u0627\u062f\u060c \u0645 \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0637\u0628\u06cc\u0639\u062a 502\u060c 340-345.<\/li>\n\n\n\n<li>Ohnishi\u060c K. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0633\u0644\u0648\u0644 156\u060c 663-677.<\/li>\n\n\n\n<li>Ocampo\u060c A. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. Cell 167, 1719-1733.e12 (2016).<\/li>\n\n\n\n<li>\u0686\u06cc\u0686\u0647\u060c A. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. Cell Stem Cell 20, 407\u2013414.e4 (2017).<\/li>\n\n\n\n<li>\u0627\u0632 \u0644\u0627\u0632\u0627\u0631\u0648\u0633\u060c I. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u0648\u0644. \u0622\u0646\u062c\u0627 27\u060c 59\u201375 (2019).<\/li>\n\n\n\n<li>\u062f\u0648\u0632\u0631\u060c \u0627\u0645. \u0633\u06cc.\u060c \u0634\u0648\u0644\u0631\u060c \u0627\u0686. \u0622\u0631 \u0648 \u0648\u0648\u060c \u0633\u0644\u0648\u0644 \u0647\u0627\u06cc \u0628\u0646\u06cc\u0627\u062f\u06cc \u062c\u06cc 36\u060c 1216-1225 (2018).<\/li>\n\n\n\n<li>\u0644\u0648\u060c \u06cc \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646 \u0637\u0628\u06cc\u0639\u062a 588\u060c 124-129.<\/li>\n\n\n\n<li>Chen, Y. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. Science 373, 1537-1540 (2021).<\/li>\n\n\n\n<li>\u0628\u0631\u0648\u062f\u0631\u060c K. C. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0646\u0627\u062a. \u067e\u06cc\u0631\u06cc 2\u060c 243-253 (2022).<\/li>\n\n\n\n<li>Chondronasiou\u060c D. et al. \u0633\u0644\u0648\u0644 \u067e\u06cc\u0631\u06cc 21\u060c e13578 (2022).<\/li>\n\n\n\n<li>\u0633\u0644\u0648\u0644\u0647\u0627\u06cc \u0628\u0646\u06cc\u0627\u062f\u06cc \u06a9\u0634\u06cc\u0634 Haridhasapavalan , K. K. , Raina , K. , Dey , C. , Adhikari , P. &amp; Thummer , R. P. \u0647\u0631\u0632\u0647. 16\u060c 56-81 (2020).<\/li>\n\n\n\n<li>\u0645\u0644\u0646\u062f\u0632\u060c \u0627\u06cc. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u062a\u0648\u0633\u0639\u0647 149, dev200361 (2022).<\/li>\n\n\n\n<li>Parras\u060c A. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0646\u0627\u062a. \u067e\u06cc\u0631\u06cc https:\/\/doi.org\/10.1038\/s43587-023-00528-5 (2022).<\/li>\n\n\n\n<li>\u06a9\u0648\u0627\u062a\u0686\u0648\u0627\u060c \u0627\u0645. \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0646\u0627\u062a. \u0645\u062a\u0627\u0628. https:\/\/doi.org\/10.1038\/s42255-023-00916-6 (2023).<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u0628\u0627 \u062a\u062c\u0632\u06cc\u0647 \u0648 \u062a\u062d\u0644\u06cc\u0644 \u0627\u062b\u0631 \u0645\u062e\u062a\u0644 \u06a9\u0631\u062f\u0646 \u0645\u06cc\u06a9\u0631\u0648\u0628\u06cc\u0648\u062a\u0627 \u062f\u0631 \u0637\u0648\u0644 \u0628\u0631\u0646\u0627\u0645\u0647 \u0631\u06cc\u0632\u06cc \u0645\u062c\u062f\u062f in vivo\u060c \u06a9\u0648\u0627\u062a\u0686\u0648\u0627 \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0646\u0634\u0627\u0646 \u062f\u0627\u062f \u06a9\u0647 \u0645\u062a\u0627\u0628\u0648\u0644\u06cc\u0633\u0645 \u0648\u0627\u0628\u0633\u062a\u0647 \u0628\u0647 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 B12 \u06cc\u06a9 \u0639\u0627\u0645\u0644 \u0645\u062d\u062f\u0648\u062f \u06a9\u0646\u0646\u062f\u0647 \u0628\u0631\u0627\u06cc \u0628\u0631\u0646\u0627\u0645\u0647 \u0631\u06cc\u0632\u06cc \u0645\u062c\u062f\u062f \u0633\u0644\u0648\u0644\u06cc \u0648 \u0627\u0646\u0639\u0637\u0627\u0641 \u067e\u0630\u06cc\u0631\u06cc \u0627\u0633\u062a \u0648 \u0645\u06a9\u0645\u0644 \u062f\u0631\u0645\u0627\u0646\u06cc \u0622\u0646 \u0631\u0627 \u0628\u0631\u0627\u06cc \u0628\u0647\u0628\u0648\u062f \u062a\u0631\u0645\u06cc\u0645 \u0628\u0627\u0641\u062a \u067e\u06cc\u0634\u0646\u0647\u0627\u062f \u0645\u06cc \u06a9\u0646\u062f. \u0628\u0631\u0646\u0627\u0645\u0647\u200c\u0631\u06cc\u0632\u06cc \u0645\u062c\u062f\u062f \u0633\u0644\u0648\u0644\u06cc \u0641\u0631\u0622\u06cc\u0646\u062f\u06cc &hellip;<\/p>\n","protected":false},"author":1,"featured_media":3695,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[20,60],"tags":[],"class_list":["post-3697","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-20","category--fa"],"_links":{"self":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts\/3697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/comments?post=3697"}],"version-history":[{"count":0,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts\/3697\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/media\/3695"}],"wp:attachment":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/media?parent=3697"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/categories?post=3697"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/tags?post=3697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}