{"id":4859,"date":"2024-04-29T17:46:23","date_gmt":"2024-04-29T17:46:23","guid":{"rendered":"https:\/\/hedayatcentre.org\/?p=4859"},"modified":"2024-04-29T18:04:30","modified_gmt":"2024-04-29T18:04:30","slug":"vitamin-d-and-marine-n-3-fatty-acids-for-autoimmune-disease-prevention-outcomes-two-years-after-completion-of-a-double-blind-placebo-controlled-trial","status":"publish","type":"post","link":"https:\/\/hedayatcentre.org\/fa\/4859\/vitamin-d-and-marine-n-3-fatty-acids-for-autoimmune-disease-prevention-outcomes-two-years-after-completion-of-a-double-blind-placebo-controlled-trial\/","title":{"rendered":"\u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 n-3 \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0628\u0631\u0627\u06cc \u067e\u06cc\u0634\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u062e\u0648\u062f \u0627\u06cc\u0645\u0646\u06cc: \u0646\u062a\u0627\u06cc\u062c \u062f\u0648 \u0633\u0627\u0644 \u067e\u0633 \u0627\u0632 \u062a\u06a9\u0645\u06cc\u0644 \u06cc\u06a9 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc \u062f\u0648\u0633\u0648\u06a9\u0648\u0631 \u0648 \u06a9\u0646\u062a\u0631\u0644\u200c\u0634\u062f\u0647 \u0628\u0627 \u062f\u0627\u0631\u0648\u0646\u0645\u0627"},"content":{"rendered":"\n

\u062e\u0644\u0627\u0635\u0647<\/strong>
\u0647\u062f\u0641: \u062f\u0631 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc 5.3 \u0633\u0627\u0644\u0647\u060c \u0641\u0627\u06a9\u062a\u0648\u0631\u06cc\u0644 2\u00d72 \u0641\u0627\u06a9\u062a\u0648\u0631\u06cc\u0644\u060c \u062f\u0648\u0633\u0648\u06a9\u0648\u0631\u060c \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0645\u06af\u0627 3 \u06a9\u0646\u062a\u0631\u0644 \u0634\u062f\u0647 \u0628\u0627 \u067e\u0644\u0627\u0633\u0628\u0648 (VITAL)\u060c \u0645\u06a9\u0645\u0644 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0628\u0627\u0639\u062b \u06a9\u0627\u0647\u0634 \u0628\u0631\u0648\u0632 \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc (AD) \u0634\u062f (\u0646\u0633\u0628\u062a \u062e\u0637\u0631 [HR] 0.78\u060c \u0641\u0627\u0635\u0644\u0647 \u0627\u0637\u0645\u06cc\u0646\u0627\u0646 95% [CI] 0.61-0.99). \u0645\u06a9\u0645\u0644 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 (n-3) \u06a9\u0627\u0647\u0634 \u0622\u0645\u0627\u0631\u06cc \u063a\u06cc\u0631 \u0642\u0627\u0628\u0644 \u062a\u0648\u062c\u0647\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u062f\u0627\u062f (HR 0.85\u060c 95% \u0641\u0627\u0635\u0644\u0647 \u0627\u0637\u0645\u06cc\u0646\u0627\u0646 (CI): 0.67-1.08). \u0647\u062f\u0641 \u0645\u0627 \u062a\u0627\u06cc\u06cc\u062f \u0645\u0648\u0627\u0631\u062f \u0628\u06cc\u0634\u062a\u0631 AD \u0646\u0627\u0634\u06cc \u0627\u0632 \u062a\u0635\u0627\u062f\u0641\u06cc\u200c\u0633\u0627\u0632\u06cc \u0648 \u067e\u0633 \u0627\u0632 \u0622\u0646 \u0648 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0627\u062b\u0631\u0627\u062a \u067e\u0627\u06cc\u062f\u0627\u0631 \u0628\u0627 \u062f\u0648 \u0633\u0627\u0644 \u0645\u0634\u0627\u0647\u062f\u0647 \u067e\u0633 \u0627\u0632 \u0645\u062f\u0627\u062e\u0644\u0647 \u0628\u0648\u062f.<\/p>\n\n\n\n

\u0631\u0648\u0634\u200c\u0647\u0627:<\/strong> \u0627\u0632 12786 \u0645\u0631\u062f 50 \u2265 \u0648 13085 \u0632\u0646 \u0628\u0627 \u0633\u0646 \u226555 \u06a9\u0647 \u062f\u0631 \u0627\u0628\u062a\u062f\u0627 \u062a\u0635\u0627\u062f\u0641\u06cc \u0634\u062f\u0646\u062f\u060c \u0634\u0631\u06a9\u062a\u200c\u06a9\u0646\u0646\u062f\u06af\u0627\u0646 \u0632\u0646\u062f\u0647 \u0648 \u0645\u0627\u06cc\u0644 \u0631\u0627 \u0628\u0631\u0627\u06cc \u062f\u0648 \u0633\u0627\u0644 \u062f\u06cc\u06af\u0631 \u0645\u0634\u0627\u0647\u062f\u0647 \u06a9\u0631\u062f\u06cc\u0645. \u0645\u0627 \u0628\u0647 \u062a\u0623\u06cc\u06cc\u062f \u0633\u0627\u0644\u0627\u0646\u0647 AD \u062c\u062f\u06cc\u062f \u06af\u0632\u0627\u0631\u0634 \u0634\u062f\u0647 \u062a\u0648\u0633\u0637 \u0634\u0631\u06a9\u062a \u06a9\u0646\u0646\u062f\u06af\u0627\u0646 \u0628\u0627 \u0628\u0631\u0631\u0633\u06cc \u067e\u0631\u0648\u0646\u062f\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0627\u062f\u0627\u0645\u0647 \u062f\u0627\u062f\u06cc\u0645. \u0645\u062f\u0644\u200c\u0647\u0627\u06cc \u06a9\u0627\u06a9\u0633\u060c HR \u0631\u0627 \u0628\u0631\u0627\u06cc \u0647\u0645\u0647 \u0631\u0648\u06cc\u062f\u0627\u062f\u0647\u0627\u06cc AD \u062a\u0623\u06cc\u06cc\u062f \u0634\u062f\u0647\u060c (\u0648 \u0646\u0642\u0627\u0637 \u067e\u0627\u06cc\u0627\u0646\u06cc \u062b\u0627\u0646\u0648\u06cc\u0647\u060c \u0627\u0632 \u062c\u0645\u0644\u0647 \u0645\u0648\u0627\u0631\u062f \u0627\u062d\u062a\u0645\u0627\u0644\u06cc\u060c \u0648 AD\u0647\u0627\u06cc \u0641\u0631\u062f\u06cc)\u060c \u062f\u0631 \u0637\u0648\u0644 \u062f\u0648\u0631\u0647\u200c\u0647\u0627\u06cc \u0645\u0634\u0627\u0647\u062f\u0647\u200c\u0627\u06cc \u0648 \u062a\u0635\u0627\u062f\u0641\u06cc \u0645\u062d\u0627\u0633\u0628\u0647 \u06a9\u0631\u062f\u0646\u062f.<\/p>\n\n\n\n

\u06cc\u0627\u0641\u062a\u0647\u200c\u0647\u0627:<\/strong> \u062f\u0631 \u0645\u062c\u0645\u0648\u0639 21592 \u0634\u0631\u06a9\u062a\u200c\u06a9\u0646\u0646\u062f\u0647 (83.5%) \u0628\u0631\u0627\u06cc \u062f\u0648 \u0633\u0627\u0644 \u062f\u06cc\u06af\u0631 \u0645\u0634\u0627\u0647\u062f\u0647 \u0634\u062f\u0646\u062f. 514 \u0634\u0631\u06a9\u062a\u200c\u06a9\u0646\u0646\u062f\u0647 \u0628\u0647 \u0628\u06cc\u0645\u0627\u0631\u06cc AD \u062a\u0627\u06cc\u06cc\u062f \u0634\u062f\u0647 \u0645\u0628\u062a\u0644\u0627 \u0634\u062f\u0646\u062f (236 \u0646\u0641\u0631 \u0627\u0632 \u06af\u0632\u0627\u0631\u0634 \u0642\u0628\u0644\u06cc)\u060c \u06a9\u0647 255 \u0646\u0641\u0631 \u0627\u0632 \u0622\u0646\u0647\u0627 \u0628\u0647\u200c\u0637\u0648\u0631 \u062a\u0635\u0627\u062f\u0641\u06cc \u0628\u0647 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062f\u0631 \u0645\u0642\u0627\u0628\u0644 259 \u0628\u0647 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u067e\u0644\u0627\u0633\u0628\u0648 (HR 0.98 [95% \u0641\u0627\u0635\u0644\u0647 \u0627\u0637\u0645\u06cc\u0646\u0627\u0646 (CI): 0.83-1.17] \u062f\u0631 7 \u0633\u0627\u0644 \u0628\u0648\u062f\u0646\u062f. AD \u062f\u0631 234 \u0634\u0631\u06a9\u062a\u200c\u06a9\u0646\u0646\u062f\u0647 \u062a\u0623\u06cc\u06cc\u062f \u0634\u062f \u06a9\u0647 \u062f\u0631 \u0627\u0628\u062a\u062f\u0627 \u0628\u0647\u200c\u0635\u0648\u0631\u062a \u062a\u0635\u0627\u062f\u0641\u06cc \u0628\u0647 n-3 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u062f\u0631 \u0645\u0642\u0627\u0628\u0644 280 \u0645\u0648\u0631\u062f \u062a\u0635\u0627\u062f\u0641\u06cc \u0628\u0627 \u062f\u0627\u0631\u0648\u0646\u0645\u0627 \u0622\u0646 (HR 0.83 [95% \u0641\u0627\u0635\u0644\u0647 \u0627\u0637\u0645\u06cc\u0646\u0627\u0646 (CI): 0.70-0.99] \u062f\u0631 7 \u0633\u0627\u0644 \u062a\u0635\u0627\u062f\u0641\u06cc \u0634\u062f\u0646\u062f. \u0627\u0632 \u0645\u0648\u0627\u0631\u062f \u062a\u0627\u06cc\u06cc\u062f \u0634\u062f\u0647 \u062c\u062f\u06cc\u062f\u060c 65 \u0645\u0648\u0631\u062f \u062f\u0631 \u0637\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc \u0633\u0627\u0632\u06cc \u0634\u0631\u0648\u0639 \u0634\u062f\u0647 \u0628\u0648\u062f\u0646\u062f. \u06af\u0646\u062c\u0627\u0646\u062f\u0646 \u0622\u0646\u0647\u0627 \u0646\u062a\u0627\u06cc\u062c \u062a\u0635\u0627\u062f\u0641\u06cc \u0634\u062f\u0647 \u0631\u0627 \u0628\u0647 \u0634\u0631\u062d \u0632\u06cc\u0631 \u062a\u063a\u06cc\u06cc\u0631 \u062f\u0627\u062f: HR 0.85 (95% CI 0.70-1.04) \u0628\u0631\u0627\u06cc \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 HR 0.87 (95% CI 0.71-1.06) \u0628\u0631\u0627\u06cc \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 n-3.<\/p>\n\n\n\n

\u0646\u062a\u06cc\u062c\u0647\u200c\u06af\u06cc\u0631\u06cc:<\/strong> \u062f\u0648 \u0633\u0627\u0644 \u067e\u0633 \u0627\u0632 \u067e\u0627\u06cc\u0627\u0646 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u060c \u0627\u062b\u0631\u0627\u062a \u0645\u062d\u0627\u0641\u0638\u062a\u06cc 2000 \u0648\u0627\u062d\u062f \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0627\u0632 \u0628\u06cc\u0646 \u0631\u0641\u062a\u060c \u0627\u0645\u0627 1000 \u0645\u06cc\u0644\u06cc\u200c\u06af\u0631\u0645 \u062f\u0631 \u0631\u0648\u0632 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 n-3 \u0627\u062b\u0631 \u067e\u0627\u06cc\u062f\u0627\u0631\u06cc \u062f\u0631 \u06a9\u0627\u0647\u0634 \u0628\u0631\u0648\u0632 AD \u062f\u0627\u0634\u062a.<\/p>\n\n\n\n

\u0645\u0646\u0627\u0628\u0639<\/h2>\n\n\n\n
    \n
  1. \u0648\u0627\u0646\u06af \u0627\u0644\u060c \u0648\u0627\u0646\u06af \u0627\u0641 \u0627\u0633\u060c \u06af\u0631\u0634\u0648\u06cc\u0646 \u0645\u06cc. \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u0627\u0646\u0633\u0627\u0646: \u0628\u0647 \u0631\u0648\u0632 \u0631\u0633\u0627\u0646\u06cc \u062c\u0627\u0645\u0639 J Intern Med 2015\u061b 278 (4): 369-395.<\/li>\n\n\n\n
  2. Jacobson DL\u060c Gange SJ\u060c Rose NR\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u067e\u06cc\u062f\u0645\u06cc\u0648\u0644\u0648\u0698\u06cc \u0648 \u0628\u0627\u0631 \u062c\u0645\u0639\u06cc\u062a\u06cc \u062a\u062e\u0645\u06cc\u0646 \u0632\u062f\u0647 \u0634\u062f\u0647 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u0645\u0646\u062a\u062e\u0628 \u062f\u0631 \u0627\u06cc\u0627\u0644\u0627\u062a \u0645\u062a\u062d\u062f\u0647 \u06a9\u0644\u06cc\u0646 \u0627\u06cc\u0645\u0648\u0646\u0648\u0644 \u0627\u06cc\u0645\u0648\u0646\u0648\u067e\u0627\u062a\u0648\u0644 1997\u061b 84 (3): 223-243.<\/li>\n\n\n\n
  3. Cotsapas C\u060c Voight BF\u060c Rossin E\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0634\u062a\u0631\u0627\u06a9 \u06af\u0630\u0627\u0631\u06cc \u0641\u0631\u0627\u06af\u06cc\u0631 \u0627\u062b\u0631\u0627\u062a \u0698\u0646\u062a\u06cc\u06a9\u06cc \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc PLoS Genet 2011\u061b 7(8):e1002254.<\/li>\n\n\n\n
  4. Conrad N\u060c Misra S\u060c Verbakel JY\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0628\u0631\u0648\u0632\u060c \u0634\u06cc\u0648\u0639 \u0648 \u0648\u0642\u0648\u0639 \u0647\u0645\u0632\u0645\u0627\u0646 \u0627\u062e\u062a\u0644\u0627\u0644\u0627\u062a \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u062f\u0631 \u0637\u0648\u0644 \u0632\u0645\u0627\u0646 \u0648 \u0628\u0631 \u0627\u0633\u0627\u0633 \u0633\u0646\u060c \u062c\u0646\u0633 \u0648 \u0648\u0636\u0639\u06cc\u062a \u0627\u062c\u062a\u0645\u0627\u0639\u06cc-\u0627\u0642\u062a\u0635\u0627\u062f\u06cc: \u06cc\u06a9 \u0645\u0637\u0627\u0644\u0639\u0647 \u06a9\u0648\u0647\u0648\u0631\u062a \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u062c\u0645\u0639\u06cc\u062a \u0631\u0648\u06cc 22 \u0645\u06cc\u0644\u06cc\u0648\u0646 \u0646\u0641\u0631 \u062f\u0631 \u0628\u0631\u06cc\u062a\u0627\u0646\u06cc\u0627. Lancet 2023\u061b 401 (10391): 1878-1890.<\/li>\n\n\n\n
  5. Roberts MH\u060c Erdei E. \u0645\u0642\u0627\u06cc\u0633\u0647 \u0646\u0631\u062e\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u0627\u06cc\u0627\u0644\u0627\u062a \u0645\u062a\u062d\u062f\u0647 \u0628\u0631\u0627\u06cc \u0633\u0627\u0644\u200c\u0647\u0627\u06cc 2010-2016 \u0628\u0631 \u0627\u0633\u0627\u0633 \u062c\u0646\u0633\u06cc\u062a\u060c \u0645\u0646\u0637\u0642\u0647 \u062c\u063a\u0631\u0627\u0641\u06cc\u0627\u06cc\u06cc\u060c \u0648 \u0646\u0698\u0627\u062f. Autoimmun Rev 2020;19(1):102423.<\/li>\n\n\n\n
  6. Al Maini M\u060c Adelowo F\u060c Al Saleh J\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0686\u0627\u0644\u0634 \u0647\u0627 \u0648 \u0641\u0631\u0635\u062a \u0647\u0627\u06cc \u062c\u0647\u0627\u0646\u06cc \u062f\u0631 \u0639\u0645\u0644 \u0631\u0648\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc: \u0645\u0642\u0627\u0644\u0647 \u0633\u0641\u06cc\u062f \u062a\u0648\u0633\u0637 \u0645\u062c\u0645\u0639 \u062c\u0647\u0627\u0646\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u0631\u0648\u0645\u0627\u062a\u06cc\u0633\u0645\u06cc \u0648 \u0627\u0633\u06a9\u0644\u062a\u06cc \u0639\u0636\u0644\u0627\u0646\u06cc. \u06a9\u0644\u06cc\u0646 \u0631\u0648\u0645\u0627\u062a\u0648\u0644 2015\u061b 34 (5): 819-829.<\/li>\n\n\n\n
  7. Sparks JA\u060c Costenbader KH. \u0698\u0646\u062a\u06cc\u06a9\u060c \u0645\u062d\u06cc\u0637 \u0648 \u062a\u0639\u0627\u0645\u0644\u0627\u062a \u0698\u0646-\u0645\u062d\u06cc\u0637 \u062f\u0631 \u0627\u06cc\u062c\u0627\u062f \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u0631\u0648\u0645\u0627\u062a\u06cc\u0633\u0645\u06cc \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 Rheum Dis Clin North Am 2014\u061b 40 (4): 637-657.<\/li>\n\n\n\n
  8. Serhan CN\u060c Clish CB\u060c Brannon J\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u062c\u0645\u0648\u0639\u0647\u200c\u0647\u0627\u06cc \u06a9\u0627\u0631\u0628\u0631\u062f\u06cc \u062c\u062f\u06cc\u062f \u0627\u0632 \u0648\u0627\u0633\u0637\u0647\u200c\u0647\u0627\u06cc \u0645\u0634\u062a\u0642 \u0634\u062f\u0647 \u0627\u0632 \u0644\u06cc\u067e\u06cc\u062f \u0628\u0627 \u0627\u062b\u0631\u0627\u062a \u0636\u062f\u0627\u0644\u062a\u0647\u0627\u0628\u06cc \u062a\u0648\u0644\u06cc\u062f \u0634\u062f\u0647 \u0627\u0632 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u0627\u0632 \u0637\u0631\u06cc\u0642 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0636\u062f\u0627\u0644\u062a\u0647\u0627\u0628\u06cc \u063a\u06cc\u0631\u0627\u0633\u062a\u0631\u0648\u0626\u06cc\u062f\u06cc \u0633\u06cc\u06a9\u0644\u0648\u0627\u06a9\u0633\u06cc\u0698\u0646\u0627\u0632 2 \u0648 \u067e\u0631\u062f\u0627\u0632\u0634 \u0628\u06cc\u0646 \u0633\u0644\u0648\u0644\u06cc. J Exp Med 2000\u061b 192 (8): 1197-1204.<\/li>\n\n\n\n
  9. Calder PC. \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0648 \u0641\u0631\u0622\u06cc\u0646\u062f\u0647\u0627\u06cc \u0627\u0644\u062a\u0647\u0627\u0628\u06cc: \u0627\u062b\u0631\u0627\u062a\u060c \u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0647\u0627 \u0648 \u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u0627\u0644\u06cc\u0646\u06cc Biochim Biophys Acta 2015\u061b 1851 (4): 469-484.<\/li>\n\n\n\n
  10. \u06cc\u0627\u0646 \u06cc\u06cc\u060c \u062c\u06cc\u0627\u0646\u06af \u062f\u0628\u0644\u06cc\u0648\u060c \u0627\u0633\u067e\u06cc\u0646\u062a\u06cc \u062a\u06cc\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u0627\u0632 \u0637\u0631\u06cc\u0642 \u0645\u0647\u0627\u0631 \u0641\u0639\u0627\u0644 \u0634\u062f\u0646 \u0627\u0644\u062a\u0647\u0627\u0628 NLRP3 \u0627\u0632 \u0627\u0644\u062a\u0647\u0627\u0628 \u0648 \u0627\u062e\u062a\u0644\u0627\u0644 \u0645\u062a\u0627\u0628\u0648\u0644\u06cc\u06a9 \u062c\u0644\u0648\u06af\u06cc\u0631\u06cc \u0645\u06cc \u06a9\u0646\u062f. \u0645\u0635\u0648\u0646\u06cc\u062a 2013\u061b 38 (6): 1154-1163.<\/li>\n\n\n\n
  11. Yamamoto E\u060c J\u00f8rgensen TN. \u0627\u062b\u0631\u0627\u062a \u0627\u06cc\u0645\u0648\u0646\u0648\u0644\u0648\u0698\u06cc\u06a9 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0631\u062a\u0628\u0627\u0637 \u0622\u0646 \u0628\u0627 \u062e\u0648\u062f \u0627\u06cc\u0645\u0646\u06cc J Autoimmun 2019\u061b 100: 7-16.<\/li>\n\n\n\n
  12. Murdaca G\u060c Tonacci A\u060c Negrini S\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0646\u0642\u0634 \u0646\u0648\u0638\u0647\u0648\u0631 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u062e\u0648\u062f \u0627\u06cc\u0645\u0646\u06cc: \u0628\u0647 \u0631\u0648\u0632 \u0631\u0633\u0627\u0646\u06cc \u062f\u0631 \u0645\u0648\u0631\u062f \u0634\u0648\u0627\u0647\u062f \u0648 \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u062f\u0631\u0645\u0627\u0646\u06cc Autoimmun Rev 2019;18(9):102350.<\/li>\n\n\n\n
  13. Fisher SA\u060c \u0631\u062d\u06cc\u0645 \u0632\u0627\u062f\u0647 M\u060c Brierley C\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0646\u0642\u0634 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062f\u0631 \u0627\u0641\u0632\u0627\u06cc\u0634 \u062a\u0639\u062f\u0627\u062f \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u062a\u0646\u0638\u06cc\u0645\u200c\u06a9\u0646\u0646\u062f\u0647 T \u062f\u0631 \u06af\u0631\u062f\u0634 \u0648 \u062a\u0639\u062f\u06cc\u0644 \u0641\u0646\u0648\u062a\u06cc\u067e\u200c\u0647\u0627\u06cc \u0633\u0644\u0648\u0644\u06cc \u062a\u0646\u0638\u06cc\u0645\u200c\u06a9\u0646\u0646\u062f\u0647 T \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0627\u0644\u062a\u0647\u0627\u0628\u06cc \u06cc\u0627 \u062f\u0631 \u062f\u0627\u0648\u0637\u0644\u0628\u0627\u0646 \u0633\u0627\u0644\u0645: \u06cc\u06a9 \u0628\u0631\u0631\u0633\u06cc \u0633\u06cc\u0633\u062a\u0645\u0627\u062a\u06cc\u06a9. PLoS One 2019; 14(9):e0222313.<\/li>\n\n\n\n
  14. Ding Y\u060c Liao W\u060c He XJ\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631\u0627\u062a 1\u060c25(OH)2D3 \u0648 \u06af\u06cc\u0631\u0646\u062f\u0647 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0628\u0631 \u0631\u0648\u06cc \u0644\u0646\u0641\u0648\u0633\u06cc\u062a \u0647\u0627\u06cc T \u062f\u0648 \u0645\u062b\u0628\u062a CD 4 +\/CD 8 + \u0645\u062d\u06cc\u0637\u06cc \u062f\u0631 \u0645\u062f\u0644 \u0645\u0648\u0634 \u0644\u0648\u067e\u0648\u0633 \u0627\u0631\u06cc\u062a\u0645\u0627\u062a\u0648\u0632 \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9. J Cell Mol Med 2017\u061b 21 (5): 975-985.<\/li>\n\n\n\n
  15. Dankers W\u060c Colin EM\u060c Van Hamburg JP\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062f\u0631 \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc: \u0645\u06a9\u0627\u0646\u06cc\u0633\u0645\u200c\u0647\u0627\u06cc \u0645\u0648\u0644\u06a9\u0648\u0644\u06cc \u0648 \u067e\u062a\u0627\u0646\u0633\u06cc\u0644 \u062f\u0631\u0645\u0627\u0646\u06cc Front Immunol 2017; 7:697.<\/li>\n\n\n\n
  16. \u06a9\u0631\u06cc\u06af\u0644 MA\u060c \u0645\u0646\u0633\u0648\u0646 \u062c\u06cc\u060c \u06a9\u0627\u0633\u062a\u0646\u0628\u0627\u062f\u0631 \u06a9.\u0627\u0686. \u0622\u06cc\u0627 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0628\u0631 \u062e\u0637\u0631 \u0627\u0628\u062a\u0644\u0627 \u0628\u0647 \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u062a\u0623\u062b\u06cc\u0631 \u0645\u06cc \u06af\u0630\u0627\u0631\u062f\u061f: \u06cc\u06a9 \u0628\u0631\u0631\u0633\u06cc \u0633\u06cc\u0633\u062a\u0645\u0627\u062a\u06cc\u06a9. Semin Arthritis Rheum 2011\u061b 40 (6): 512-531.e8.<\/li>\n\n\n\n
  17. Kremer JM\u060c Lawrence DA\u060c Jubiz W\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u0635\u0631\u0641 \u0645\u06a9\u0645\u0644 \u0631\u0648\u063a\u0646 \u0645\u0627\u0647\u06cc \u0648 \u0631\u0648\u063a\u0646 \u0632\u06cc\u062a\u0648\u0646 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645\u0627\u062a\u0648\u0626\u06cc\u062f \u0627\u062b\u0631\u0627\u062a \u0628\u0627\u0644\u06cc\u0646\u06cc \u0648 \u0627\u06cc\u0645\u0648\u0646\u0648\u0644\u0648\u0698\u06cc\u06a9 \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645 1990\u061b 33 (6): 810-820.<\/li>\n\n\n\n
  18. Geusens P\u060c Wouters C\u060c Nijs J\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631 \u0637\u0648\u0644\u0627\u0646\u06cc \u0645\u062f\u062a \u0645\u06a9\u0645\u0644 \u0627\u0633\u06cc\u062f \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u062f\u0631 \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645\u0627\u062a\u0648\u0626\u06cc\u062f \u0641\u0639\u0627\u0644 \u06cc\u06a9 \u0645\u0637\u0627\u0644\u0639\u0647 12 \u0645\u0627\u0647\u0647\u060c \u062f\u0648\u0633\u0648\u06a9\u0648\u0631\u060c \u06a9\u0646\u062a\u0631\u0644 \u0634\u062f\u0647. \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645 1994\u061b 37 (6): 824-829.<\/li>\n\n\n\n
  19. Sperling RI\u060c Weinblatt M\u060c Robin JL\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631\u0627\u062a \u0645\u06a9\u0645\u0644 \u063a\u0630\u0627\u06cc\u06cc \u0628\u0627 \u0631\u0648\u063a\u0646 \u0645\u0627\u0647\u06cc \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0628\u0631 \u062a\u0648\u0644\u06cc\u062f \u0648 \u0639\u0645\u0644\u06a9\u0631\u062f \u0648\u0627\u0633\u0637\u0647 \u0644\u06cc\u067e\u06cc\u062f \u0644\u06a9\u0648\u0633\u06cc\u062a\u06cc \u062f\u0631 \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645\u0627\u062a\u0648\u0626\u06cc\u062f. \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645 1987\u061b 30 (9): 988-997.<\/li>\n\n\n\n
  20. \u0647\u0627\u0646 \u062c\u06cc\u060c \u06a9\u0648\u06a9 \u0627\u0646 \u0622\u0631\u060c \u0627\u0644\u06a9\u0633\u0627\u0646\u062f\u0631 EK\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u06a9\u0645\u0644 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0648 \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u0631\u062e \u062f\u0627\u062f\u0647: \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc \u06a9\u0646\u062a\u0631\u0644 \u0634\u062f\u0647 VITAL. BMJ 2022;376:e066452.<\/li>\n\n\n\n
  21. \u0645\u0646\u0633\u0648\u0646 JE\u060c \u06a9\u0648\u06a9 NR\u060c \u0644\u06cc IM\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 n-3 \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0648 \u067e\u06cc\u0634\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u0642\u0644\u0628\u06cc \u0639\u0631\u0648\u0642\u06cc \u0648 \u0633\u0631\u0637\u0627\u0646. N Engl J Med 2019\u061b 380 (1): 23-32.<\/li>\n\n\n\n
  22. \u0645\u0646\u0633\u0648\u0646 JE\u060c \u06a9\u0648\u06a9 NR\u060c \u0644\u06cc IM\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u06a9\u0645\u0644 \u0647\u0627\u06cc \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u067e\u06cc\u0634\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0633\u0631\u0637\u0627\u0646 \u0648 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u0642\u0644\u0628\u06cc \u0639\u0631\u0648\u0642\u06cc. N Engl J Med 2019\u061b 380 (1): 33-44.<\/li>\n\n\n\n
  23. Bassuk SS\u060c Manson JE\u060c Lee IM\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0648\u06cc\u0698\u06af\u06cc \u0647\u0627\u06cc \u067e\u0627\u06cc\u0647 \u0634\u0631\u06a9\u062a \u06a9\u0646\u0646\u062f\u06af\u0627\u0646 \u062f\u0631 \u0622\u0632\u0645\u0627\u06cc\u0634 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0645\u06af\u0627-3 (VITAL). Contemp Clin Trials 2016\u061b 47:235-243.<\/li>\n\n\n\n
  24. Althouse AD, Below JE, Claggett BL, et al. \u062a\u0648\u0635\u06cc\u0647 \u0647\u0627\u06cc\u06cc \u0628\u0631\u0627\u06cc \u06af\u0632\u0627\u0631\u0634 \u0622\u0645\u0627\u0631\u06cc \u062f\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0642\u0644\u0628 \u0648 \u0639\u0631\u0648\u0642: \u06af\u0632\u0627\u0631\u0634 \u0648\u06cc\u0698\u0647 \u0627\u0632 \u0627\u0646\u062c\u0645\u0646 \u0642\u0644\u0628 \u0622\u0645\u0631\u06cc\u06a9\u0627. \u062a\u06cc\u0631\u0627\u0698 2021\u061b 144 (4): e70-e91.<\/li>\n\n\n\n
  25. Ceglia L\u060c Nelson J\u060c Ware J\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u06cc\u0646 \u0648\u0632\u0646 \u0628\u062f\u0646 \u0648 \u062a\u0631\u06a9\u06cc\u0628 \u0648 \u0633\u0637\u062d 25 \u0647\u06cc\u062f\u0631\u0648\u06a9\u0633\u06cc \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u067e\u0644\u0627\u0633\u0645\u0627 \u062f\u0631 \u0628\u0631\u0646\u0627\u0645\u0647 \u067e\u06cc\u0634\u06af\u06cc\u0631\u06cc \u0627\u0632 \u062f\u06cc\u0627\u0628\u062a. Eur J Nutr 2017\u061b 56 (1): 161-170.<\/li>\n\n\n\n
  26. Young KA\u060c Engelman CD\u060c Langefeld CD\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0631\u062a\u0628\u0627\u0637 \u0633\u0637\u062d \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u067e\u0644\u0627\u0633\u0645\u0627 \u0628\u0627 \u0686\u0627\u0642\u06cc \u062f\u0631 \u0622\u0645\u0631\u06cc\u06a9\u0627\u06cc\u06cc \u0647\u0627\u06cc \u0627\u0633\u067e\u0627\u0646\u06cc\u0627\u06cc\u06cc \u062a\u0628\u0627\u0631 \u0648 \u0622\u0641\u0631\u06cc\u0642\u0627\u06cc\u06cc \u062a\u0628\u0627\u0631. J Clin Endocrinol Metab 2009\u061b 94 (9): 3306-3313.<\/li>\n\n\n\n
  27. Gangloff A\u060c Bergeron J\u060c Pelletier-Beaumont E\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631 \u06a9\u0627\u0647\u0634 \u062d\u062c\u0645 \u0628\u0627\u0641\u062a \u0686\u0631\u0628\u06cc \u0628\u0631 \u0633\u0637\u0648\u062d 25 \u0647\u06cc\u062f\u0631\u0648\u06a9\u0633\u06cc \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062f\u0631 \u06af\u0631\u062f\u0634: \u0646\u062a\u06cc\u062c\u0647 \u06cc\u06a9 \u0645\u062f\u0627\u062e\u0644\u0647 \u0633\u0628\u06a9 \u0632\u0646\u062f\u06af\u06cc 1 \u0633\u0627\u0644\u0647 \u062f\u0631 \u0645\u0631\u062f\u0627\u0646 \u0686\u0627\u0642 \u0627\u062d\u0634\u0627\u06cc\u06cc. Int J Obes (Land) 2015\u061b 39 (11): 1638-1643.<\/li>\n\n\n\n
  28. Arnson Y\u060c Amital H\u060c Shoenfeld Y. \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc: \u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0627\u062a\u06cc\u0648\u0644\u0648\u0698\u06cc\u06a9\u06cc \u0648 \u062f\u0631\u0645\u0627\u0646\u06cc \u062c\u062f\u06cc\u062f. Ann Rheum Dis 2007\u061b 66 (9): 1137-1142.<\/li>\n\n\n\n
  29. Cantorna MT\u060c Mahon BD. \u0634\u0648\u0627\u0647\u062f \u062f\u0631 \u062d\u0627\u0644 \u0627\u0641\u0632\u0627\u06cc\u0634 \u0628\u0631\u0627\u06cc \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u06cc\u06a9 \u0639\u0627\u0645\u0644 \u0645\u062d\u06cc\u0637\u06cc \u0645\u0648\u062b\u0631 \u0628\u0631 \u0634\u06cc\u0648\u0639 \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc Exp Biol Med (Maywood) 2004\u061b 229 (11): 1136-1142.<\/li>\n\n\n\n
  30. \u062f\u0648\u0686\u0631\u062e\u0647 DD. \u0645\u062a\u0627\u0628\u0648\u0644\u06cc\u0633\u0645 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D\u060c \u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0627\u062b\u0631\u060c \u0648 \u06a9\u0627\u0631\u0628\u0631\u062f\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc. Chem Biol 2014\u061b 21 (3): 319-329.<\/li>\n\n\n\n
  31. \u0642\u0631\u06cc\u0634\u06cc SA\u060c Camargo CA Jr. \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062f\u0631 \u0627\u0633\u062a\u0631\u0633 \u062d\u0627\u062f \u0648 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0628\u062d\u0631\u0627\u0646\u06cc. Curr Opin Clin Nutr Metab Care 2012\u061b 15 (6): 625-634.<\/li>\n\n\n\n
  32. Brot C\u060c J\u00f8rgensen NR\u060c Sorensen OH. \u062a\u0627\u062b\u06cc\u0631 \u0633\u06cc\u06af\u0627\u0631 \u0628\u0631 \u0648\u0636\u0639\u06cc\u062a \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0645\u062a\u0627\u0628\u0648\u0644\u06cc\u0633\u0645 \u06a9\u0644\u0633\u06cc\u0645 Eur J Clin Nutr 1999\u061b 53 (12): 920-926.<\/li>\n\n\n\n
  33. Freedman BI, Register TC. \u062a\u0623\u062b\u06cc\u0631 \u0646\u0698\u0627\u062f \u0648 \u0698\u0646\u062a\u06cc\u06a9 \u0628\u0631 \u0645\u062a\u0627\u0628\u0648\u0644\u06cc\u0633\u0645 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D\u060c \u0633\u0644\u0627\u0645\u062a \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0648 \u0639\u0631\u0648\u0642. Nat Rev Nephrol 2012\u061b 8 (8): 459-466.<\/li>\n\n\n\n
  34. Costenbader KH\u060c MacFarlane LA\u060c Lee IM\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631\u0627\u062a \u06cc\u06a9 \u0633\u0627\u0644 \u0645\u06a9\u0645\u0644 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0628\u0631 \u0646\u0634\u0627\u0646\u06af\u0631\u0647\u0627\u06cc \u0632\u06cc\u0633\u062a\u06cc \u0627\u0644\u062a\u0647\u0627\u0628 \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9 \u062f\u0631 \u0628\u0632\u0631\u06af\u0633\u0627\u0644\u0627\u0646 \u0645\u0633\u0646 \u0627\u06cc\u0627\u0644\u0627\u062a \u0645\u062a\u062d\u062f\u0647. Clin Chem 2019\u061b 65 (12): 1508-1521.<\/li>\n\n\n\n
  35. \u062f\u0648\u0646\u06af \u06cc\u06cc\u060c \u0698\u0648 \u0627\u0686\u060c \u0686\u0646 \u0627\u0644\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631\u0627\u062a \u0645\u06a9\u0645\u0644 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D3 \u0648 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u062f\u0631\u06cc\u0627\u06cc\u06cc \u0628\u0631 \u0646\u0634\u0627\u0646\u06af\u0631\u0647\u0627\u06cc \u0632\u06cc\u0633\u062a\u06cc \u0627\u0644\u062a\u0647\u0627\u0628 \u0633\u06cc\u0633\u062a\u0645\u06cc\u06a9: \u06cc\u0627\u0641\u062a\u0647\u200c\u0647\u0627\u06cc 4 \u0633\u0627\u0644\u0647 \u0627\u0632 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc VITAL. \u0645\u0648\u0627\u062f \u0645\u063a\u0630\u06cc 2022\u061b 14 (24): 5307.<\/li>\n\n\n\n
  36. Chitranjali T\u060c Anoop Chandran P\u060c Muraleedhara Kurup G. \u06a9\u0646\u0633\u0627\u0646\u062a\u0631\u0647 \u0627\u0633\u06cc\u062f \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u0627\u0632 Dunaliella salina \u062f\u0627\u0631\u0627\u06cc \u062e\u0648\u0627\u0635 \u0636\u062f \u0627\u0644\u062a\u0647\u0627\u0628\u06cc \u0627\u0632 \u062c\u0645\u0644\u0647 \u0645\u0633\u062f\u0648\u062f \u06a9\u0631\u062f\u0646 \u0627\u0646\u062a\u0642\u0627\u0644 \u0647\u0633\u062a\u0647 NF-\u03baB \u0627\u0633\u062a. \u0627\u06cc\u0645\u0648\u0646\u0648\u0641\u0627\u0631\u0645\u0627\u06a9\u0644 \u0627\u06cc\u0645\u0648\u0646\u0648\u062a\u0648\u06a9\u0633\u06cc\u06a9\u0648\u0644 2015\u061b 37 (1): 81-89.<\/li>\n\n\n\n
  37. Kliewer SA\u060c Sundseth SS\u060c Jones SA\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0648 \u0627\u06cc\u06a9\u0648\u0632\u0627\u0646\u0648\u0626\u06cc\u062f\u0647\u0627 \u0628\u06cc\u0627\u0646 \u0698\u0646 \u0631\u0627 \u0627\u0632 \u0637\u0631\u06cc\u0642 \u0628\u0631\u0647\u0645\u06a9\u0646\u0634 \u0645\u0633\u062a\u0642\u06cc\u0645 \u0628\u0627 \u06af\u06cc\u0631\u0646\u062f\u0647 \u0647\u0627\u06cc \u03b1 \u0648 \u03b3 \u0641\u0639\u0627\u0644 \u0634\u062f\u0647 \u062a\u0648\u0633\u0637 \u067e\u0631\u0627\u06a9\u0633\u06cc \u0632\u0648\u0645 \u062a\u0646\u0638\u06cc\u0645 \u0645\u06cc \u06a9\u0646\u0646\u062f. Proc Natl Acad Sci U S A 1997;94(9):4318-4323.<\/li>\n\n\n\n
  38. Forman BM\u060c Chen J\u060c Evans RM. \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u06cc\u067e\u0648\u0644\u06cc\u067e\u06cc\u062f\u0645\u06cc\u06a9\u060c \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u063a\u06cc\u0631\u0627\u0634\u0628\u0627\u0639 \u0686\u0646\u062f\u06af\u0627\u0646\u0647 \u0648 \u0627\u06cc\u06a9\u0648\u0632\u0627\u0646\u0648\u0626\u06cc\u062f\u0647\u0627 \u0644\u06cc\u06af\u0627\u0646\u062f\u0647\u0627\u06cc \u06af\u06cc\u0631\u0646\u062f\u0647 \u0647\u0627\u06cc \u03b1 \u0648 \u03b4 \u0641\u0639\u0627\u0644 \u0634\u062f\u0647 \u062a\u0648\u0633\u0637 \u067e\u0631\u0627\u06a9\u0633\u06cc \u0632\u0648\u0645 \u0647\u0633\u062a\u0646\u062f. Proc Natl Acad Sci U S A 1997;94(9):4312-4317.<\/li>\n\n\n\n
  39. Novak TE\u060c Babcock TA\u060c Jho DH\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u0647\u0627\u0631 NF-kB \u062a\u0648\u0633\u0637 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u03c9-3\u060c \u0631\u0648\u0646\u0648\u06cc\u0633\u06cc TNF-\u03b1 \u0645\u0627\u06a9\u0631\u0648\u0641\u0627\u0698 \u062a\u062d\u0631\u06cc\u06a9 \u0634\u062f\u0647 \u0628\u0627 LPS \u0631\u0627 \u062a\u0639\u062f\u06cc\u0644 \u0645\u06cc \u06a9\u0646\u062f. Am J Physiol Lung Cell Mol Physiol 2003\u061b 284(1):L84-L89.<\/li>\n\n\n\n
  40. Zhao Y\u060c Joshi-Barve S\u060c Barve S\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u06cc\u06a9\u0648\u0632\u0627\u067e\u0646\u062a\u0627\u0646\u0648\u0626\u06cc\u06a9 \u0627\u0633\u06cc\u062f \u0628\u0627 \u062c\u0644\u0648\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0641\u0639\u0627\u0644 \u0634\u062f\u0646 NF-kB \u0627\u0632 \u0628\u06cc\u0627\u0646 TNF-\u03b1 \u0646\u0627\u0634\u06cc \u0627\u0632 LPS \u062c\u0644\u0648\u06af\u06cc\u0631\u06cc \u0645\u06cc \u06a9\u0646\u062f. J Am Coll Nutr 2004\u061b 23 (1): 71-78.<\/li>\n\n\n\n
  41. \u0647\u0627\u0633\u0644\u06cc \u062f\u0628\u0644\u06cc\u0648 \u062c\u06cc\u060c \u0641\u0631\u0646\u0627\u0646\u062f\u0632 \u0627\u0633 \u062f\u06cc\u060c \u0648\u0631\u0627 \u06a9\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0646\u0648\u0627\u0639 \u0698\u0646\u062a\u06cc\u06a9\u06cc \u0645\u0631\u062a\u0628\u0637 \u0628\u0627 \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc\u060c \u0633\u06cc\u06af\u0646\u0627\u0644 \u062f\u0647\u06cc NF\u03baB \u0648 \u067e\u0627\u0633\u062e \u0628\u0647 \u0645\u062d\u0631\u06a9 \u0647\u0627\u06cc \u0627\u0644\u062a\u0647\u0627\u0628\u06cc \u0631\u0627 \u0647\u062f\u0627\u06cc\u062a \u0645\u06cc \u06a9\u0646\u0646\u062f. Sci Transl Med 2015;7(291):291ra93.<\/li>\n\n\n\n
  42. \u0633\u06cc\u0645\u0648\u067e\u0648\u0644\u0648\u0633 AP. \u062c\u0646\u0628\u0647 \u0647\u0627\u06cc \u062a\u06a9\u0627\u0645\u0644\u06cc \u0631\u0698\u06cc\u0645 \u063a\u0630\u0627\u06cc\u06cc\u060c \u0646\u0633\u0628\u062a \u0627\u0645\u06af\u0627 6 \/ \u0627\u0645\u06af\u0627 3 \u0648 \u062a\u0646\u0648\u0639 \u0698\u0646\u062a\u06cc\u06a9\u06cc: \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u062a\u063a\u0630\u06cc\u0647 \u0627\u06cc \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc \u0647\u0627\u06cc \u0645\u0632\u0645\u0646 Biomed Pharmacother 2006\u061b 60 (9): 502-507.<\/li>\n\n\n\n
  43. Larsson SC\u060c Kumlin M\u060c Ingelman-Sundberg M\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0628\u0627 \u0632\u0646\u062c\u06cc\u0631\u0647 \u0628\u0644\u0646\u062f n-3 \u0631\u0698\u06cc\u0645 \u063a\u0630\u0627\u06cc\u06cc \u0628\u0631\u0627\u06cc \u067e\u06cc\u0634\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0633\u0631\u0637\u0627\u0646: \u0628\u0631\u0631\u0633\u06cc \u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0647\u0627\u06cc \u0628\u0627\u0644\u0642\u0648\u0647 Am J Clin Nutr 2004\u061b 79 (6): 935-945.<\/li>\n\n\n\n
  44. Serhan CN\u060c Chiang N\u060c Dalli J. \u06a9\u062f \u062a\u0641\u06a9\u06cc\u06a9 \u0627\u0644\u062a\u0647\u0627\u0628 \u062d\u0627\u062f: \u0648\u0627\u0633\u0637\u0647\u200c\u0647\u0627\u06cc \u0644\u06cc\u067e\u06cc\u062f\u06cc \u062c\u062f\u06cc\u062f \u062f\u0631 \u0648\u0636\u0648\u062d. Semin Immunol 2015\u061b 27 (3): 200-215.<\/li>\n\n\n\n
  45. \u0686\u06cc\u0627\u0646\u06af \u0646\u060c \u0633\u0631\u0647\u0627\u0646 \u0633\u06cc.\u0627\u0646. \u0634\u0628\u06a9\u0647 \u0645\u06cc\u0627\u0646\u062c\u06cc \u062a\u062e\u0635\u0635\u06cc \u0637\u0631\u0641\u062f\u0627\u0631 \u062d\u0644 \u0648 \u0641\u0635\u0644: \u0628\u0647 \u0631\u0648\u0632 \u0631\u0633\u0627\u0646\u06cc \u062f\u0631 \u0645\u0648\u0631\u062f \u062a\u0648\u0644\u06cc\u062f \u0648 \u0627\u0642\u062f\u0627\u0645\u0627\u062a. \u0645\u0642\u0627\u0644\u0627\u062a \u0628\u06cc\u0648\u0634\u06cc\u0645\u06cc 2020\u061b 64 (3): 443-462.<\/li>\n\n\n\n
  46. Kremer JM\u060c Lawrence DA\u060c Petrillo GF\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0627\u062b\u0631\u0627\u062a \u0631\u0648\u063a\u0646 \u0645\u0627\u0647\u06cc \u0628\u0627 \u062f\u0648\u0632 \u0628\u0627\u0644\u0627 \u0628\u0631 \u0631\u0648\u0645\u0627\u062a\u06cc\u0633\u0645 \u0645\u0641\u0635\u0644\u06cc \u067e\u0633 \u0627\u0632 \u0642\u0637\u0639 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0636\u062f\u0627\u0644\u062a\u0647\u0627\u0628\u06cc \u063a\u06cc\u0631\u0627\u0633\u062a\u0631\u0648\u0626\u06cc\u062f\u06cc. \u0647\u0645\u0628\u0633\u062a\u06af\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0648 \u0627\u06cc\u0645\u0646\u06cc. \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645 1995\u061b 38 (8): 1107-1114.<\/li>\n\n\n\n
  47. Kremer JM\u060c Jubiz W\u060c Michalek A\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u0645\u06a9\u0645\u0644 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0631\u0648\u063a\u0646 \u0645\u0627\u0647\u06cc \u062f\u0631 \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645\u0627\u062a\u0648\u0626\u06cc\u062f \u0641\u0639\u0627\u0644 \u06cc\u06a9 \u0645\u0637\u0627\u0644\u0639\u0647 \u062f\u0648\u0633\u0648\u06a9\u0648\u0631\u060c \u06a9\u0646\u062a\u0631\u0644 \u0634\u062f\u0647\u060c \u0645\u062a\u0642\u0627\u0637\u0639. Ann Intern Med 1987\u061b 106 (4): 497-503.<\/li>\n\n\n\n
  48. \u0631\u062c\u0627\u06cc\u06cc \u0639\u060c \u0645\u0648\u0644\u0627 \u06a9\u060c \u0642\u0631\u0628\u0627\u0646\u06cc \u0639\u060c \u0648 \u0647\u0645\u06a9\u0627\u0631\u0627\u0646. \u062a\u0623\u062b\u06cc\u0631 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0622\u0631\u062a\u0631\u06cc\u062a \u0631\u0648\u0645\u0627\u062a\u0648\u0626\u06cc\u062f \u0641\u0639\u0627\u0644 \u06a9\u0647 \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 DMARDs \u062f\u0631\u06cc\u0627\u0641\u062a \u0645\u06cc \u06a9\u0646\u0646\u062f: \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc \u06a9\u0646\u062a\u0631\u0644 \u0634\u062f\u0647 \u062f\u0648\u0633\u0648\u06a9\u0648\u0631. Glob J Health Sci 2015\u061b 8 (7): 18-25.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    \u062e\u0644\u0627\u0635\u0647\u0647\u062f\u0641: \u062f\u0631 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc 5.3 \u0633\u0627\u0644\u0647\u060c \u0641\u0627\u06a9\u062a\u0648\u0631\u06cc\u0644 2\u00d72 \u0641\u0627\u06a9\u062a\u0648\u0631\u06cc\u0644\u060c \u062f\u0648\u0633\u0648\u06a9\u0648\u0631\u060c \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0648 \u0627\u0645\u06af\u0627 3 \u06a9\u0646\u062a\u0631\u0644 \u0634\u062f\u0647 \u0628\u0627 \u067e\u0644\u0627\u0633\u0628\u0648 (VITAL)\u060c \u0645\u06a9\u0645\u0644 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u0628\u0627\u0639\u062b \u06a9\u0627\u0647\u0634 \u0628\u0631\u0648\u0632 \u0628\u06cc\u0645\u0627\u0631\u06cc \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc (AD) \u0634\u062f (\u0646\u0633\u0628\u062a \u062e\u0637\u0631 [HR] 0.78\u060c \u0641\u0627\u0635\u0644\u0647 \u0627\u0637\u0645\u06cc\u0646\u0627\u0646 95% [CI] 0.61-0.99). \u0645\u06a9\u0645\u0644 \u0627\u0633\u06cc\u062f\u0647\u0627\u06cc \u0686\u0631\u0628 \u0627\u0645\u06af\u0627 3 (n-3) \u06a9\u0627\u0647\u0634 \u0622\u0645\u0627\u0631\u06cc \u063a\u06cc\u0631 \u0642\u0627\u0628\u0644 \u062a\u0648\u062c\u0647\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u062f\u0627\u062f (HR 0.85\u060c …<\/p>\n","protected":false},"author":1,"featured_media":4857,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[20,60],"tags":[],"class_list":["post-4859","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-20","category--fa"],"_links":{"self":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts\/4859","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/comments?post=4859"}],"version-history":[{"count":2,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts\/4859\/revisions"}],"predecessor-version":[{"id":4864,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/posts\/4859\/revisions\/4864"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/media\/4857"}],"wp:attachment":[{"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/media?parent=4859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/categories?post=4859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hedayatcentre.org\/fa\/wp-json\/wp\/v2\/tags?post=4859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}